The Future of Anti-Inflammatory Medicines
Early anti-inflammatory medicines, such as aspirin and ibuprofen, transformed the treatment of pain and sore joints. However, more powerful and precisely targeted therapies are still needed for serious inflammatory diseases. To date, biologics, including antibodies that require injection or infusion, have been the primary treatment option. We are developing small molecules designed to deliver the precision and potency of biologics with the convenience of oral medicines.
Our Mission
Sitala is dedicated to improving people’s lives by transforming the treatment of autoimmune and inflammatory diseases. We target the “first responder” cells and innate immune pathways that drive chronic inflammation. With a focus on orally available medicines, such as tablets or capsules, we aim to address critical treatment gaps for patients living with debilitating autoimmune and inflammatory diseases.
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The Challenge of Treating Inflammation
When immune cells recognize an infection or harmful substance, they trigger short-term, beneficial inflammation that helps restore the body to health. In chronic diseases, however, immune cells can become overactive, driving sustained inflammation that damages healthy tissues. We need precision medicines that can cool these “hot” immune cells while preserving the beneficial parts of the immune system that help fight infection.
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Our Approach
We are targeting key pathways that drive harmful inflammation with orally available medicines designed to be convenient and safe for patients. Our precision medicines specifically inhibit either complement factor B, or Target X, both of which are implicated in rare and major inflammatory diseases. By targeting essential components of the innate immune response, we aim to move beyond symptom relief and address the underlying drivers of degenerative inflammatory and autoimmune diseases.
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The Pipeline
We work to advance scientific discoveries rapidly from the lab to the clinic, translating innovation into meaningful benefits for patients as quickly as possible. Learn more about our pipeline of potential medicines for patients in need.
Find out more about our drug pipeline
Invest in Transforming Healthcare
Our approach has the potential to radically change the lives of patients with inadequate current therapies. We have attracted investment from leading healthcare industry investors. Join us in our mission to improve lives of people with inflammatory diseases.
Interested in finding out more about our therapies in development?
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Get in touch
Collaborating with Sitala offers an opportunity to be part of cutting-edge science that could transform the lives of patients worldwide. We welcome partnering interest from academia, biotech and pharma. We also welcome career enquires from motivated individuals looking to work in a dynamic and fast-moving, small team environment.